Considerable efforts have been made to investigate individual differences as well as characteristics of the trauma itself that both may contribute to the development of PTSD. However, only a small proportion develop Posttraumatic Stress Disorder (PTSD) (5.6%). Treatment effects on PTSD symptoms correlated positively with activation in the left superior temporal gyrus, and superior/middle frontal gyrus.īEP induced clinical recovery in PTSD patients, and appeared to modulate the functioning of specific PTSD-related sites in the prefrontal cortical regions.Īpproximately 70% of the general population experience a traumatic event during lifetime. After effective psychotherapy, lower activation was measured in the right middle frontal gyrus, compared to the PTSD patients on the waiting list. ![]() PTSD patients treated with BEP significantly improved on all PTSD symptom clusters compared to those on the waiting list. ![]() Treatment was brief eclectic psychotherapy (BEP) in 16 weekly individual sessions.Īt baseline, greater activation was found in the right insula and right superior/middle frontal gyrus in the PTSD group than in the control group. All 20 out-patients were randomly assigned to treatment or wait-list conditions. Cerebral blood flow was measured using trauma script-driven imagery during 99mtechnetium hexamethyl-propylene-amine-oxime single-photon emission computed tomography scanning. ![]() Twenty civilian PTSD out-patients and 15 traumatized control subjects were assessed at baseline using psychometric ratings. Effects of psychotherapy on these brain regions have not yet been examined. ![]() Functional brain-imaging studies in post-traumatic stress disorder (PTSD) have suggested functional alterations in temporal and prefrontal cortical regions.
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